Why mixing substances increases risk

Watch for dangerous combinations

Opioids combined with alcohol or sedating medicines can dangerously slow breathing. Examples of sedating medicines include some sleeping pills and benzodiazepines. A stimulant does not cancel out a depressant or make someone safe to drive.

Ask before combining

• Tell a pharmacist or clinician about prescriptions, over-the-counter medicines, supplements, alcohol, and other substances.
• Ask: “Could this combination affect my breathing, alertness, or heart?”
• Take medicines as prescribed and do not share them.
• Avoid adding another substance to manage an unwanted effect.

If something goes wrong

Difficulty waking, abnormal breathing, chest pain, or a seizure requires emergency help. Tell responders what may have been taken, including approximate timing if known. You do not need a complete list before calling.

If you are helping someone

Help someone check interactions with a pharmacist; do not suggest a substance to counteract another.

WARN (OTHERS)

After immediate care is covered, share dated advisories or observed concerns. Say what is confirmed and what is uncertain. Protect people’s privacy.

Emergency care comes first. Never share someone’s name, identifying photo or private health details.